The aortic sinuses (sinuses of Valsalva) are three small bulges in the wall of the aorta just above the aortic valve, one behind each cusp. The right and left coronary arteries arise from the right and left sinuses, so the coronaries fill when the valve closes.
| Location | Root of the ascending aorta, immediately above the aortic valve cusps |
|---|---|
| Parts |
|
| Nerve Supply | Cardiac plexus |
| Blood Supply | Vasa vasorum of the aortic root |
| Venous drainage |
|
| Lymphatic drainage |
|
Give origin to the coronary arteries and help the valve cusps close smoothly by creating eddies behind them.
Dilatation of the aortic root, as in Marfan syndrome or with a bicuspid valve, is measured at the sinuses on echocardiography and guides timing of surgery. A ruptured sinus of Valsalva aneurysm causes sudden heart failure. Anomalous origin of a coronary artery from the wrong sinus is a known cause of sudden death in young athletes.
Enlargement of the sinuses that may lead to aortic regurgitation or dissection, common in Marfan syndrome.
Thinning and bulging of one sinus that can rupture into a heart chamber.
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