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Home › Body Atlas › Brain & Spinal Cord › Cornu Ammonis
Brain Structure Head & Skull

Cornu Ammonis

cornu ammonis

Cornu Ammonis (Ammon horn) is the hippocampus proper, a curled band of three-layered cortex divided into fields CA1 to CA4. Together with the dentate gyrus it forms the classic seahorse shape seen in cross-section.

Anatomical Data

Structure & Connections

LocationFloor of the inferior horn of the lateral ventricle, medial temporal lobe
Parts
  • CA1 (Sommer sector)
  • CA2
  • CA3
  • CA4 (hilus)
  • Pyramidal cell layer
  • Alveus
Connections
Blood SupplyPosterior cerebral artery (hippocampal branches); Anterior choroidal artery
Biomechanics

Function & Actions

Forms and consolidates new memories of facts and events and maps space; CA3 links patterns and CA1 sends output.

Clinical Relevance

Clinical Notes

CA1 neurons are very sensitive to low oxygen and die first after cardiac arrest, causing memory loss. In mesial temporal sclerosis, scarring of CA1 and CA4 causes drug-resistant epilepsy, which may be cured by surgery.

Pathology

Common Injuries & Conditions

Mesial Temporal Sclerosis

Neuron loss and scarring of the hippocampus, the commonest cause of drug-resistant epilepsy in adults.

Hypoxic Amnesia

Memory loss after cardiac arrest or near drowning from death of CA1 neurons.

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