The cingulum is a long association bundle lying within the cingulate gyrus and continuing into the parahippocampal gyrus. It arches around the corpus callosum from the frontal lobe to the medial temporal lobe. It connects parts of the limbic system and is part of the Papez circuit.
| Location | Within the cingulate gyrus and parahippocampal gyrus, encircling the corpus callosum |
|---|---|
| Parts |
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| Connections |
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| Blood Supply | Anterior cerebral artery; Posterior cerebral artery |
Links the cingulate cortex with the medial temporal lobe and prefrontal cortex, supporting memory, attention and emotion.
Cingulum damage is linked to memory, attention and emotional problems, and its integrity declines early in Alzheimer disease. Cingulotomy, a small surgical lesion of the anterior cingulum and gyrus, has been used for intractable pain and severe obsessive compulsive disorder. It is also studied in depression and post-traumatic stress disorder.
Early loss of cingulum integrity, especially the posterior part, linked to memory decline.
Changes in mood, attention or pain perception after surgical lesioning of the anterior cingulum.
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