Denonvilliers fascia (rectoprostatic fascia) is a thin but tough membranous layer between the back of the prostate and seminal vesicles and the front of the rectum. It is thought to form from the fused walls of the deepest part of the rectovesical pouch in the fetus. In females the matching layer is the rectovaginal septum.
| Location | Male pelvis, between the back of the prostate and seminal vesicles and the front of the rectum |
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Separates the prostate and seminal vesicles from the rectum, acting as a barrier to the spread of disease and as the anterior plane in rectal and prostate surgery.
Denonvilliers fascia is the critical surgical plane landmark in radical prostatectomy, total mesorectal excision for rectal cancer, and repair of rectovaginal fistula. In TME, the anterior dissection plane on the posterior surface of Denonvilliers fascia protects the cavernous nerves of Walsh (neurovascular bundle) that lie immediately posterolateral. In prostatectomy, the choice of whether to incise anterior or posterior to the fascia determines whether the neurovascular bundle is preserved for erectile function.
The cavernous nerves for erection run posterolateral to the prostate along Denonvilliers fascia; nerve-sparing prostatectomy incises the fascia on the prostatic side, leaving the neurovascular bundle on the rectal side, while non-nerve-sparing surgery removes the fascia with the specimen to clear positive margins.
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