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Home › Body Atlas › Organs › Gallbladder
Organ Abdomen

Gallbladder

vesica biliaris

The gallbladder is a pear-shaped sac, about 7-10 cm long, that lies in a fossa on the underside of the liver. It stores and concentrates the bile made by the liver and holds about 30-50 mL. It has a fundus, body and neck, and its neck continues as the cystic duct.

Anatomical Data

Structure & Supply

LocationIn the gallbladder fossa on the visceral surface of the liver, between the right lobe and the quadrate lobe; fundus near the tip of the right ninth costal cartilage
Parts
Nerve SupplyCoeliac plexus (sympathetic and visceral pain); Vagus nerve (parasympathetic); Right phrenic nerve (referred shoulder pain)
Blood SupplyCystic artery (usually from the right hepatic artery)
Venous drainage
  • Cystic veins to the liver and hepatic portal vein
Lymphatic drainage
  • Cystic node
  • Hepatic nodes
  • Coeliac nodes
Biomechanics

Function & Actions

Stores bile between meals, concentrates it by absorbing water and salts, and contracts in response to cholecystokinin to release it into the duodenum.

Clinical Relevance

Clinical Notes

Its fundus lies behind the tip of the right ninth costal cartilage, where tenderness on deep breathing (Murphy sign) suggests acute cholecystitis. Gallstones are very common, especially with age, female sex and obesity, and cause biliary colic, cholecystitis, cholangitis or pancreatitis. Pain from the gallbladder can be referred to the right shoulder tip via the phrenic nerve.

Pathology

Common Injuries & Conditions

Gallstones

Hardened deposits of cholesterol or bile pigment that may be silent or cause biliary colic when they block the gallbladder neck.

Acute Cholecystitis

Inflammation of the gallbladder, usually from a stone blocking the cystic duct, causing constant right upper quadrant pain, fever and a positive Murphy sign.

Gallbladder Carcinoma

Uncommon aggressive cancer linked to long-standing gallstones, often found late or incidentally after cholecystectomy.

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