The gallbladder is a pear-shaped sac, about 7-10 cm long, that lies in a fossa on the underside of the liver. It stores and concentrates the bile made by the liver and holds about 30-50 mL. It has a fundus, body and neck, and its neck continues as the cystic duct.
| Location | In the gallbladder fossa on the visceral surface of the liver, between the right lobe and the quadrate lobe; fundus near the tip of the right ninth costal cartilage |
|---|---|
| Parts |
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| Nerve Supply | Coeliac plexus (sympathetic and visceral pain); Vagus nerve (parasympathetic); Right phrenic nerve (referred shoulder pain) |
| Blood Supply | Cystic artery (usually from the right hepatic artery) |
| Venous drainage |
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| Lymphatic drainage |
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Stores bile between meals, concentrates it by absorbing water and salts, and contracts in response to cholecystokinin to release it into the duodenum.
Its fundus lies behind the tip of the right ninth costal cartilage, where tenderness on deep breathing (Murphy sign) suggests acute cholecystitis. Gallstones are very common, especially with age, female sex and obesity, and cause biliary colic, cholecystitis, cholangitis or pancreatitis. Pain from the gallbladder can be referred to the right shoulder tip via the phrenic nerve.
Hardened deposits of cholesterol or bile pigment that may be silent or cause biliary colic when they block the gallbladder neck.
Inflammation of the gallbladder, usually from a stone blocking the cystic duct, causing constant right upper quadrant pain, fever and a positive Murphy sign.
Uncommon aggressive cancer linked to long-standing gallstones, often found late or incidentally after cholecystectomy.
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