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Home › Body Atlas › Organs › Anterior Mediastinum
Organ Chest

Anterior Mediastinum

mediastinum anterius

The anterior mediastinum is the narrow space between the back of the sternum and the front of the pericardium. In adults it contains mainly fat, connective tissue, lymph nodes and remnants of the thymus. In children, the much larger thymus fills it.

Anatomical Data

Structure & Supply

LocationInferior mediastinum, between the body of the sternum and the fibrous pericardium, below the plane of the sternal angle.
Parts
  • Thymic remnant (lower part)
  • Sternopericardial ligaments
  • Fat and loose connective tissue
  • Anterior mediastinal (parasternal) lymph nodes
  • Branches of the internal thoracic vessels
Blood SupplyInternal thoracic arteries (perforating and mediastinal branches)
Lymphatic drainage
  • Parasternal nodes
  • Anterior mediastinal nodes
Biomechanics

Function & Actions

Provides a padded space between the sternum and heart and contains lymph nodes draining the front of the chest.

Clinical Relevance

Clinical Notes

Masses in the front of the mediastinum are classically remembered as the 'four Ts': thymoma, teratoma and other germ cell tumours, thyroid enlargement extending down, and lymphoma. Radiologists often use a broader prevascular compartment that includes the thymus in the superior mediastinum. Large anterior masses can compress the airway or heart, especially when the patient lies flat or is anaesthetised.

Pathology

Common Injuries & Conditions

Thymoma

A tumour of thymic epithelial cells, often linked with myasthenia gravis. It may be found incidentally or cause chest pain and cough.

Mediastinal Lymphoma

Lymphoma presenting as an anterior mediastinal mass, especially Hodgkin lymphoma in young adults. It can cause cough, breathlessness and night sweats.

Mediastinal Germ Cell Tumour

Tumours such as teratoma or seminoma arising from misplaced germ cells. They mainly affect young men.

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