The submandibular space is the paired space below the mylohyoid muscle, containing the submandibular gland, lymph nodes, and fatty tissue. It communicates with the sublingual space above the mylohyoid and with the lateral pharyngeal space posteriorly. The submandibular duct (Wharton duct) from the submandibular gland traverses upward through the mylohyoid to open in the floor of the mouth.
Ludwig angina is a rapidly progressive bilateral submandibular (and sublingual and submental) space infection, typically from mandibular molar periapical infection. It produces woody firm indurated swelling of the floor of the mouth, trismus, drooling, and potentially fatal airway compromise. Emergency management includes early awake fibreoptic intubation or surgical airway before floor of mouth swelling obliterates landmarks, IV penicillin with metronidazole, and surgical decompression of all three floor of mouth spaces.
Bilateral submandibular, sublingual, and submental space infection from mandibular molar infection produces rapidly progressive floor of mouth induration, tongue elevation, trismus, and drooling with airway compromise; management requires emergency airway before sedation, IV antibiotics, and wide surgical decompression of all three spaces bilaterally.
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