The deep posterior compartment of the leg lies deep to the transverse intermuscular septum and contains tibialis posterior, flexor digitorum longus, flexor hallucis longus, the tibial nerve, and the posterior tibial artery. It is enclosed by the tibia medially, fibula laterally, interosseous membrane anteriorly, and the transverse septum posteriorly.
The deep posterior compartment is the most frequently missed compartment in lower leg fasciotomy and has the greatest consequence if undertreated, as its contents are critical for ankle and toe function. Pressure monitoring via a Stryker device placed through the transverse septum is required for accurate assessment. Chronic exertional deep posterior compartment syndrome is the most common cause of medial tibial shin pain in runners after excluding tibial stress injury.
Pressure elevation causing tibialis posterior, FDL, and FHL ischaemia and tibial nerve compression, producing foot inversion weakness, toe flexor loss, and plantar anaesthesia.
Exercise-induced reversible pressure elevation producing medial shin pain that begins after a consistent distance and resolves within 30 minutes of rest, diagnosed by post-exercise intracompartmental pressure.
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