The atlanto-odontoid space (atlantodental interval, ADI) is the distance between the posterior surface of the anterior arch of C1 and the anterior surface of the odontoid process, measured on a lateral cervical spine X-ray. Normal ADI is 3 mm or less in adults and 5 mm or less in children. The transverse atlantal ligament fills this space between the dens and the anterior arch.
The ADI is the primary radiographic measure of atlantoaxial instability. An ADI greater than 3 mm in adults indicates transverse ligament incompetence from trauma, rheumatoid arthritis, or Down syndrome. The posterior atlanto-odontoid interval (PADI — space available for the cord) is equally important: less than 14 mm indicates cord compromise risk. Flexion-extension lateral X-rays dynamically assess ADI change. Pre-operative ADI measurement is mandatory before any procedure requiring neck manipulation or positioning.
Atlantodental interval exceeding 3 mm from transverse ligament incompetence in rheumatoid arthritis, Down syndrome, or trauma, producing risk of spinal cord compression with neck movement requiring surgical C1-C2 fusion.
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