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Home › Body Atlas › Glands & Lymphatics › Sentinel Lymph Node
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Sentinel Lymph Node

nodus lymphoideus sentinelis

A sentinel lymph node is the first node or nodes that lymph, and therefore cancer cells, reach from a tumour. It is not a fixed anatomical node but is identified for each patient by tracer or dye.

Anatomical Data

Structure & Secretions

LocationVaries with the tumour site; most often in the axilla for breast cancer and the groin, axilla or neck for melanoma
Receives lymph from
  • Lymph from the tumour area
Lymphatic drainage
  • Next tier of regional lymph nodes
Biomechanics

Function & Actions

Acts as the first filter for lymph from a given area of tissue.

Clinical Relevance

Clinical Notes

Sentinel node biopsy is standard for staging breast cancer and melanoma: if the sentinel node is free of cancer, the remaining nodes are very likely clear and full node removal can be avoided, which greatly reduces lymphoedema and shoulder problems.

Pathology

Common Injuries & Conditions

Sentinel Node Metastasis

Cancer found in the first draining node, guiding further surgery or treatment.

Lymphoedema After Node Surgery

Swelling of the limb after lymph nodes are removed, less common with sentinel biopsy alone.

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