A sentinel lymph node is the first node or nodes that lymph, and therefore cancer cells, reach from a tumour. It is not a fixed anatomical node but is identified for each patient by tracer or dye.
| Location | Varies with the tumour site; most often in the axilla for breast cancer and the groin, axilla or neck for melanoma |
|---|---|
| Receives lymph from |
|
| Lymphatic drainage |
|
Acts as the first filter for lymph from a given area of tissue.
Sentinel node biopsy is standard for staging breast cancer and melanoma: if the sentinel node is free of cancer, the remaining nodes are very likely clear and full node removal can be avoided, which greatly reduces lymphoedema and shoulder problems.
Cancer found in the first draining node, guiding further surgery or treatment.
Swelling of the limb after lymph nodes are removed, less common with sentinel biopsy alone.
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