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Home › Body Atlas › Brain & Spinal Cord › Ventricular System
Brain Structure Head & Skull

Ventricular System

systema ventriculare encephali

The ventricular system is a set of four connected cavities inside the brain that make cerebrospinal fluid and channel it through the brain. Fluid made mostly by the choroid plexus flows from the two lateral ventricles to the third ventricle, through the cerebral aqueduct to the fourth ventricle, and then out into the subarachnoid space. It continues down as the central canal of the spinal cord.

Anatomical Data

Structure & Connections

LocationWithin the brain: lateral ventricles in the cerebral hemispheres, third ventricle in the diencephalon, cerebral aqueduct in the midbrain and fourth ventricle between the pons, medulla and cerebellum
Parts
Connections
  • Subarachnoid space and cisterns (via the fourth ventricle apertures)
  • Central canal of the spinal cord
  • Arachnoid granulations and venous sinuses (via the subarachnoid space)
Blood SupplyAnterior choroidal artery; Posterior choroidal arteries; Posterior inferior cerebellar artery (fourth ventricle choroid plexus)
Biomechanics

Function & Actions

Produces and circulates cerebrospinal fluid, which cushions the brain, keeps its chemical environment stable and removes waste.

Clinical Relevance

Clinical Notes

A blockage anywhere in the ventricular system causes obstructive (non-communicating) hydrocephalus, with enlargement of the ventricles above the block. Impaired absorption causes communicating hydrocephalus. Treatments include ventriculoperitoneal shunts, external ventricular drains and endoscopic third ventriculostomy. Ventricle size on imaging is a key indicator of raised pressure or brain atrophy.

Pathology

Common Injuries & Conditions

Obstructive Hydrocephalus

Build-up of cerebrospinal fluid above a blockage in the ventricular system, causing headache, vomiting, drowsiness and papilloedema.

Normal Pressure Hydrocephalus

Enlarged ventricles in older adults with gait disturbance, urinary incontinence and cognitive decline, sometimes improved by shunting.

Intraventricular Haemorrhage

Bleeding into the ventricles, common in premature infants and after adult brain haemorrhage, which can block CSF flow.

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