The cerebral aqueduct, or aqueduct of Sylvius, is a narrow channel about 15 mm long running through the midbrain from the third ventricle to the fourth ventricle. It is the narrowest part of the ventricular system, which makes it the most common site of blockage causing hydrocephalus.
| Location | Midbrain, between the tectum behind and the tegmentum in front, surrounded by the periaqueductal grey |
|---|---|
| Parts |
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| Connections |
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| Blood Supply | Midbrain perforating branches of the posterior cerebral and superior cerebellar arteries (surrounding tissue) |
Carries cerebrospinal fluid from the third ventricle to the fourth ventricle.
Aqueductal stenosis, congenital or acquired from tumours, haemorrhage or infection, enlarges the lateral and third ventricles while the fourth ventricle stays normal. Endoscopic third ventriculostomy bypasses the blocked aqueduct. Phase-contrast MRI measures CSF flow through the aqueduct.
Narrowing or blockage of the aqueduct causing hydrocephalus of the lateral and third ventricles, presenting as a large head in infants or headache in adults.
Compression of the aqueduct by a tectal glioma or pineal tumour, causing obstructive hydrocephalus.
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