The subfornical organ is a small circumventricular organ on the front wall of the third ventricle beneath the fornix, near the interventricular foramen. It lacks a blood brain barrier and detects circulating angiotensin II.
| Location | Roof of the third ventricle, just below the fornix and near the interventricular foramina |
|---|---|
| Parts |
|
| Connections |
|
| Blood Supply | Choroidal branches of the anterior and posterior circulations |
Triggers thirst and vasopressin release in response to angiotensin II, helping restore blood volume and pressure.
It links the renin-angiotensin system with thirst and is thought to contribute to the intense thirst of blood loss and dehydration. It may play a role in some forms of high blood pressure.
Excessive drinking that can arise from disturbed signalling in thirst circuits including the subfornical organ.
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