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Home › Body Atlas › Brain & Spinal Cord › Septum Pellucidum
Brain Structure Head & Skull

Septum Pellucidum

septum pellucidum

The septum pellucidum is a thin, two-layered vertical sheet that separates the front parts of the right and left lateral ventricles. It stretches from the underside of the corpus callosum down to the fornix.

Anatomical Data

Structure & Connections

LocationMidline, between the frontal horns and bodies of the lateral ventricles, below the corpus callosum and above the fornix
Parts
  • Two thin laminae
  • Occasional fluid space between them (cavum septi pellucidi)
Connections
Blood SupplyAnterior cerebral artery (septal branches); Anterior communicating artery perforators
Biomechanics

Function & Actions

Acts as a partition between the lateral ventricles and carries some fibres linking the hippocampus and septal area.

Clinical Relevance

Clinical Notes

A small fluid gap between its layers (cavum septi pellucidi) is normal in newborns and often persists harmlessly, but a large persistent cavum is more common in boxers and others with repeated head impacts. Absence of the septum occurs in septo-optic dysplasia, with poor vision and pituitary problems. Shift of the septum on scans shows midline shift from a mass or bleed.

Pathology

Common Injuries & Conditions

Septo-Optic Dysplasia

Developmental absence of the septum with underdeveloped optic nerves and pituitary hormone deficiency.

Cavum Septi Pellucidi

A fluid space between the layers, usually a normal variant, more common after repetitive head trauma.

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