The portal vein carries nutrient-rich blood from the entire gastrointestinal tract and spleen to the liver for processing before it enters the systemic circulation. Portal hypertension from liver cirrhosis or portal vein obstruction raises portal venous pressure, producing varices at portosystemic anastomoses (oesophageal, haemorrhoidal, and periumbilical caput medusae) where portal blood can bypass the liver into systemic veins.
| Origin | Junction of the superior mesenteric vein and splenic vein posterior to the pancreatic neck |
|---|
Portal hypertension causes oesophageal varices that rupture to produce massive upper gastrointestinal bleeding with 30 to 40 percent mortality per episode. Management includes variceal band ligation, terlipressin, Sengstaken-Blakemore tube tamponade for acute haemorrhage, and TIPS (transjugular intrahepatic portosystemic shunt) for refractory cases. Portal vein thrombosis can complicate pancreatitis, malignancy, and hypercoagulable states, producing mesenteric ischaemia and portal hypertension.
Increased portal venous pressure from cirrhosis or portal obstruction producing oesophageal varices, splenomegaly, and ascites managed with beta-blockers, band ligation, and TIPS for refractory cases.
This website uses cookies to enhance your experience. Some are essential for site functionality, while others help us analyze and improve your usage experience. Please review your options and make your choice.
If you are under 16 years old, please ensure that you have received consent from your parent or guardian for any non-essential cookies.
Your privacy is important to us. You can adjust your cookie settings at any time. For more information about how we use data, please read our privacy policy. You may change your preferences at any time by clicking on the settings button below.
Note that if you choose to disable some types of cookies, it may impact your experience of the site and the services we are able to offer.
Some required resources have been blocked, which can affect third-party services and may cause the site to not function properly.
This website uses cookies to enhance your browsing experience and ensure the site functions properly. By continuing to use this site, you acknowledge and accept our use of cookies.