The adrenal glands have a single dominant draining vein on each side with asymmetric anatomy. The right adrenal vein is short (5-10 mm) and drains directly and posterolaterally into the right IVC. The left adrenal vein is longer and typically joins the left renal vein rather than draining to the IVC directly. Both veins receive contributions from inferior phrenic veins, and their anatomy is highly variable.
The right adrenal vein's extremely short course from the adrenal gland directly to the posterolateral IVC makes right adrenalectomy the technically more demanding side, as inadvertent avulsion causes major IVC bleeding. In phaeochromocytoma surgery, early ligation of the adrenal vein before tumour manipulation is mandatory to prevent catecholamine surge. Adrenal vein sampling (AVS) is the gold standard test for primary hyperaldosteronism, distinguishing unilateral from bilateral adrenal adenoma by comparing aldosterone-to-cortisol ratios from each adrenal vein catheterised separately.
Selective cannulation of each adrenal vein with simultaneous cortisol-corrected aldosterone sampling distinguishes a unilateral Conn adenoma (lateralisation index greater than 4:1) from bilateral hyperplasia, guiding whether surgical adrenalectomy or medical management with aldosterone antagonists is appropriate.
The right adrenal vein's direct short drainage into the posterolateral IVC means inadvertent avulsion during right adrenalectomy causes difficult haemorrhage from the IVC wall, requiring immediate proximal-distal caval clamping and primary suture repair.
This website uses cookies to enhance your experience. Some are essential for site functionality, while others help us analyze and improve your usage experience. Please review your options and make your choice.
If you are under 16 years old, please ensure that you have received consent from your parent or guardian for any non-essential cookies.
Your privacy is important to us. You can adjust your cookie settings at any time. For more information about how we use data, please read our privacy policy. You may change your preferences at any time by clicking on the settings button below.
Note that if you choose to disable some types of cookies, it may impact your experience of the site and the services we are able to offer.
Some required resources have been blocked, which can affect third-party services and may cause the site to not function properly.
This website uses cookies to enhance your browsing experience and ensure the site functions properly. By continuing to use this site, you acknowledge and accept our use of cookies.