The six extensor compartments are separated by fibrous septa from the extensor retinaculum, each with a specific anatomical relationship. From radial to ulnar: 1st (de Quervain's site), 2nd (second extensor compartment syndrome), 3rd (EPL around Lister's tubercle), 4th (most common extensor tenosynovitis zone), 5th (EDM — sagittal band pathology), 6th (ECU — subsheath tears).
Each compartment guides its tendons in specific directions across the wrist — the compartment anatomy determines the pattern of tenosynovitis and tendon pathology
Intersection syndrome occurs at the crossing of the first and second compartment tendons 4-6 cm proximal to Lister's tubercle — the APL and EPB of the first compartment cross over the ECRL and ECRB of the second, producing friction tenosynovitis at the crossing point. Repetitive rowing, weight training, and cycling are common causes. Rest, splinting, and corticosteroid injection resolve most cases.
First-second extensor compartment crossing tenosynovitis 4-6 cm proximal to Lister's tubercle producing dorsal forearm pain managed with rest, splint, and injection.
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