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Home › Body Atlas › Organs › Interatrial Septum
Organ Chest

Interatrial Septum

septum interatriale

The interatrial septum is the thin wall separating the right and left atria. It runs obliquely, facing forwards and to the right, and its most visible feature on the right side is the fossa ovalis, the remnant of the fetal foramen ovale. Defects in this wall are among the most common congenital heart problems found in adults.

Anatomical Data

Structure & Supply

LocationBetween the right and left atria, angled so that the left atrium lies behind and to the left of the right atrium.
Parts
Nerve SupplyCardiac plexus; Vagus nerves (parasympathetic, slows rate); Sympathetic cardiac nerves from cervical and upper thoracic (T1-T4) ganglia (raise rate and force)
Blood SupplyRight coronary artery (atrial branches); Left circumflex artery (atrial branches)
Biomechanics

Function & Actions

Separates oxygen-poor blood in the right atrium from oxygen-rich blood in the left atrium after birth. Before birth the foramen ovale in this septum lets oxygenated placental blood bypass the lungs.

Clinical Relevance

Clinical Notes

Atrial septal defects allow left-to-right shunting that overloads the right heart and pulmonary circulation, often unnoticed until adulthood. The septum is deliberately punctured (transseptal puncture) to reach the left atrium during ablation for atrial fibrillation and other catheter procedures. Lipomatous hypertrophy of the septum is a benign fatty thickening seen on imaging.

Pathology

Common Injuries & Conditions

Atrial Septal Defect

A hole in the septum, most often of the secundum type at the fossa ovalis. Large defects cause right heart enlargement, arrhythmias and pulmonary hypertension and can be closed with a catheter device or surgery.

Patent Foramen Ovale

Failure of the flap of the foramen ovale to seal after birth, present in about a quarter of adults. It can allow clots to cross into the systemic circulation and is linked to some strokes and decompression illness in divers.

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