Descending the anterior arm through pronator teres and the carpal tunnel to supply thenar muscles and the lateral 3.5 digits — the most commonly compressed peripheral nerve.
Carpal tunnel syndrome affects up to 3% of the population. Tinel's and Phalen's are classical tests. Proximal compression at pronator teres produces anterior forearm aching with resisted pronation.
Nocturnal paraesthesia in thumb, index, middle, and radial ring fingers with thenar atrophy in advanced cases — the most common peripheral nerve entrapment.
Median nerve entrapment at pronator teres producing forearm aching and hand paraesthesia reproduced by resisted pronation with extended elbow.
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