The largest branch of the lumbar plexus (L2–L4), descending beneath the inguinal ligament to supply the anterior thigh muscles and medial leg skin via the saphenous nerve.
Palsy produces quadriceps weakness, absent knee jerk, and anterior thigh numbness. Retroperitoneal haematoma must be excluded urgently in anticoagulated patients.
Quadriceps weakness, absent knee reflex, and anterior thigh numbness from inguinal or retroperitoneal compression.
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