The trigeminal nerve is the largest cranial nerve, providing sensation to the entire face and motor supply to the muscles of mastication. Trigeminal neuralgia (tic douloureux) produces the most severe pain known to medicine — brief electric-shock pains in the V2 or V3 distribution triggered by light touch (washing, eating, talking). Microvascular decompression of the nerve root at the pons (Jannetta procedure) provides definitive surgical cure in 80-85%.
| Origin | Trigeminal ganglion (semilunar ganglion of Gasser) in Meckel's cave on the petrous bone apex |
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Trigeminal neuralgia is diagnosed clinically by its characteristic lancinating pain in the V2-V3 distribution with a trigger zone. MRI with FIESTA sequences shows neurovascular conflict at the nerve root entry zone. Carbamazepine is first-line. MVD is the most effective long-term treatment; stereotactic radiosurgery (Gamma Knife) provides non-invasive but less durable relief.
Trigeminal nerve root compression producing lancinating facial pain managed with carbamazepine or microvascular decompression.
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