The transverse mesocolon is a broad peritoneal fold connecting the transverse colon to the posterior abdominal wall along the anterior surface of the pancreas, containing the middle colic artery, vein, and lymphatics.
Suspends the transverse colon, transmits its blood supply and lymphatic drainage, forms the floor of the lesser sac below the pancreas, and divides the peritoneal cavity into supramolic and inframesolic compartments.
The transverse mesocolon root marks the anterior surface of the pancreatic neck and body — the landmark for division during Whipple pancreaticoduodenectomy. Mesenteric adenopathy in the transverse mesocolon may represent gastric, colonic, or pancreatic cancer lymph node spread. Congenital mesocolic hernias through the transverse mesocolon produce internal herniation.
The mesocolon root is divided during pancreaticoduodenectomy to expose the neck of the pancreas and the superior mesenteric vein.
Bowel herniation through a defect in the transverse mesocolon producing acute small bowel obstruction, managed by emergency laparoscopic or open reduction.
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