The interosseous membrane of the leg is a strong fibrous sheet stretched between the interosseous borders of the tibia and fibula, with most fibres running downward and laterally from tibia to fibula. It separates the anterior compartment from the deep posterior compartment and gives origin to muscles of both. An opening near its upper end transmits the anterior tibial vessels, and distally it continues into the interosseous ligament of the tibiofibular syndesmosis.
| Origin | Interosseous border of the tibia |
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| Insertion | Interosseous border of the fibula, the dense fibrous membrane between the two leg bones |
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Binds the tibia and fibula together, transmits load between them and provides attachment for leg muscles.
The membrane is torn in Maisonneuve injuries, where an external rotation force fractures the proximal fibula and the tear runs down to a disrupted ankle syndesmosis; the ankle mortise is unstable despite no distal fibular fracture and needs syndesmotic fixation. It also forms part of the walls of the anterior and deep posterior compartments, so it is relevant to compartment syndrome. In four-compartment fasciotomy each compartment's fascia, including the deep posterior compartment, must be released.
Proximal fibular fracture with interosseous membrane and syndesmosis tear producing an unstable ankle mortise, treated with syndesmotic screw or suture button fixation.
Raised pressure in the compartments the membrane helps enclose, usually after fracture or crush injury, treated by urgent four-compartment fasciotomy.
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