The interosseous talocalcaneal ligament fills the tarsal sinus (the space between the talus and calcaneus) and is the primary stabiliser of the subtalar joint, providing resistance to inversion and anterior translation of the talus on the calcaneus. Its position in the tarsal sinus is clinically significant because sinus tarsi syndrome — chronic lateral hindfoot pain from tarsal sinus pathology — involves this ligament and its surrounding synovial tissue.
| Origin | Sulcus tali on the inferior talus |
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| Insertion | Sulcus calcanei on the superior calcaneus |
| Actions | The strongest subtalar ligament — occupies the tarsal sinus and strongly stabilises the subtalar joint against inversion |
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Sinus tarsi syndrome produces lateral hindfoot pain in the area of the tarsal sinus anterior to the lateral malleolus, reproduced by direct palpation in the sinus and by hindfoot inversion. MRI identifies signal changes in the interosseous talocalcaneal ligament and adjacent tissue in sinus tarsi syndrome. Corticosteroid injection into the tarsal sinus confirms the diagnosis and provides relief.
Interosseous talocalcaneal ligament and tarsal sinus soft tissue injury producing lateral hindfoot pain after ankle sprain, confirmed by tarsal sinus injection and managed with injection and physiotherapy.
