The parasternal (internal thoracic or internal mammary) lymph nodes are small nodes lying along the internal thoracic vessels just inside the chest wall, beside the sternum. They drain the inner parts of the breast and the anterior chest and upper abdominal walls.
| Location | Along the internal thoracic artery and vein, at the anterior ends of the intercostal spaces, deep to the costal cartilages beside the sternum |
|---|---|
| Receives lymph from |
|
| Lymphatic drainage |
|
Filter lymph from the medial breast and anterior thoracic and abdominal walls.
Breast cancers in the medial half of the breast can spread to these nodes, which are not palpable and are assessed by imaging or occasionally by sentinel node mapping. They may be included in radiotherapy fields for breast cancer. Lymph can cross to the opposite side through these nodes.
Spread of breast cancer, usually from medial tumours, to the parasternal chain, upstaging the disease.
Involvement of parasternal nodes in Hodgkin lymphoma with anterior mediastinal disease.
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