The internal iliac lymph nodes lie along the internal iliac vessels and their branches deep in the pelvis. They drain most of the pelvic organs, the deep perineum and the gluteal region.
| Location | Along the internal iliac artery and its branches on the posterolateral pelvic wall |
|---|---|
| Receives lymph from |
|
| Lymphatic drainage |
Filter lymph from the pelvic organs, perineum and buttock.
These nodes are a major route of spread for cancers of the cervix, prostate, bladder and lower rectum, and are included in pelvic node dissection and pelvic radiotherapy. Enlarged internal iliac nodes can compress the sacral plexus, causing leg pain. They are not palpable but may be detected on MRI or PET.
Spread of cervical carcinoma to internal iliac and obturator nodes, influencing staging and treatment.
Spread of prostate cancer to internal iliac nodes, detected with PSMA PET imaging.
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