The semimembranosus-tibial collateral bursa lies between the semimembranosus tendon and the posterior surface of the tibial collateral (medial collateral) ligament at the posteromedial knee. It is distinct from the semimembranosus-gastrocnemius bursa (the primary Baker cyst precursor) and from the pes anserinus bursa. Inflammation produces posteromedial knee pain specifically aggravated by knee flexion and internal tibial rotation.
This bursa is one of several bursae at the posteromedial knee that can be a source of medial knee pain in runners and cyclists. It is identified on MRI as fluid between the semimembranosus tendon and the MCL in the posteromedial corner. Treatment follows the principles of other posteromedial knee bursitis: activity modification, physiotherapy including medial hamstring stretching, and ultrasound-guided corticosteroid injection.
Semimembranosus-tibial collateral bursa inflammation produces posteromedial knee pain and swelling, distinguished from pes anserinus bursitis by its higher and more posterior location and its specific aggravation by resisted knee flexion with internal rotation, managed with injection and physiotherapy.
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