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Home › Body Atlas › Brain & Spinal Cord › Preoptic Area
Brain Structure Head & Skull

Preoptic Area

area preoptica

The preoptic area is the front-most part of the hypothalamus, just above the optic chiasm and near the lamina terminalis. It contains nuclei that control body temperature, sleep and reproduction.

Anatomical Data

Structure & Connections

LocationAnterior hypothalamus, around the front of the third ventricle above the optic chiasm
Parts
  • Medial preoptic nucleus
  • Median preoptic nucleus
  • Ventrolateral preoptic nucleus
  • Sexually dimorphic nucleus
Connections
Blood SupplyAnterior cerebral and anterior communicating artery perforators
Biomechanics

Function & Actions

Sets body temperature, promotes sleep, regulates fluid balance and controls GnRH release for reproduction.

Clinical Relevance

Clinical Notes

It acts as the body thermostat; fever reflects a raised set point here. Damage can cause insomnia or abnormal temperature control, and it is involved in heat illness during exercise in hot conditions.

Pathology

Common Injuries & Conditions

Hypothalamic Thermoregulation Failure

Poor temperature control after damage to the preoptic area.

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