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Brain Structure Head & Skull

Longitudinal Cerebral Fissure

fissura longitudinalis cerebri

The longitudinal cerebral fissure is the deep midline cleft that separates the left and right cerebral hemispheres. It contains the falx cerebri, a fold of dura, and the anterior cerebral arteries. At its depth, in the middle part, the hemispheres are joined by the corpus callosum.

Anatomical Data

Structure & Connections

LocationMidline of the brain, between the two cerebral hemispheres
Connections
Blood SupplyAnterior cerebral arteries (pericallosal and callosomarginal branches)
Biomechanics

Function & Actions

Separates the two hemispheres and houses the falx cerebri and the anterior cerebral arteries.

Clinical Relevance

Clinical Notes

The interhemispheric fissure is a common surgical route to the corpus callosum, third ventricle and anterior communicating artery. Masses on one side push the cingulate gyrus under the falx (subfalcine herniation), which may compress the anterior cerebral artery. Blood along the fissure on CT may indicate subarachnoid haemorrhage or an interhemispheric subdural haematoma.

Pathology

Common Injuries & Conditions

Subfalcine Herniation

Displacement of brain tissue under the falx cerebri across the midline from an expanding mass.

Parafalcine Meningioma

A tumour arising from the falx within the fissure, which may compress both medial hemispheres.

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