Lister's tubercle is the prominent dorsal ridge on the distal radius that acts as a pulley for the extensor pollicis longus tendon as it changes direction from the posterior forearm to the radial wrist. It is the key landmark dividing the second (ECRL/ECRB) from the third (EPL) extensor compartments.
Lister's tubercle is the anatomical landmark used for placement of dorsal wrist arthroscopy portals — the 3-4 portal is just radial to the tubercle between EPL and EDC. EPL rupture at Lister's tubercle occurs in distal radius fractures and rheumatoid tenosynovitis, treated by EIP tendon transfer. The tubercle may be fractured in shear-type distal radius fractures and is identifiable on lateral wrist X-ray.
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