The cuboid is on the lateral side of the midfoot, articulating with the calcaneus, lateral cuneiform, navicular, and the bases of the fourth and fifth metatarsals. It forms the cuboid tunnel through which the peroneus longus tendon passes on its way to the medial foot.
The cuboid forms the lateral column of the midfoot and the lateral boundary of the Lisfranc joint. The peroneus longus tendon passes through the cuboid groove on its plantar surface, which can trap the tendon during lateral ankle injuries, producing cuboid syndrome of lateral midfoot pain from peroneus longus entrapment. Nutcracker fractures of the cuboid between the calcaneus and metatarsal bases occur in midfoot crush injuries and can be missed on plain radiographs.
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