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Home › Body Atlas › Sense Organs › Olfactory Receptor Neurons
Sense Organ Head & Skull

Olfactory Receptor Neurons

neurona receptoria olfactoria

Olfactory receptor neurons are the smell-detecting nerve cells in the roof of the nasal cavity. Each carries hair-like cilia bearing one type of odour receptor, and their axons pass through the cribriform plate to the olfactory bulb.

Anatomical Data

Structure & Supply

LocationOlfactory epithelium on the roof of the nasal cavity, upper septum and superior concha
Parts
  • Dendritic knob with cilia
  • Cell body
  • Unmyelinated axons forming olfactory nerve filaments
  • Basal stem cells that replace them
Nerve SupplyOlfactory nerve (cranial nerve I)
Blood SupplyAnterior and posterior ethmoidal arteries; Sphenopalatine artery
Biomechanics

Function & Actions

Detect odour molecules and send signals to the olfactory bulb.

Clinical Relevance

Clinical Notes

They are among the few neurons replaced throughout life. Viral infections, including COVID-19, head injury tearing their axons at the cribriform plate, and ageing all reduce smell. Loss of smell can be an early sign of Parkinson and Alzheimer disease.

Pathology

Common Injuries & Conditions

Anosmia

Loss of smell from infection, head injury, sinus disease or neurodegeneration.

Post-Traumatic Olfactory Loss

Shearing of olfactory axons through the cribriform plate after a blow to the head.

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