Thymic (Hassall) corpuscles are rounded, onion-like whorls of flattened epithelial cells found in the thymic medulla. They are a hallmark feature that identifies the thymus under the microscope.
| Location | Medulla of the thymus |
|---|---|
| Secretes |
|
| Nerve Supply | Vagus nerve; Cervicothoracic sympathetic chain |
| Blood Supply | Internal thoracic artery branches; Inferior thyroid artery branches |
| Venous drainage |
|
| Lymphatic drainage |
|
Help mature dendritic cells and support the development of regulatory T cells.
They are used by pathologists to recognise thymic tissue and their number increases with age and in some immune disorders.
Enlargement of the thymus with lymphoid follicles, often seen in myasthenia gravis.
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