Delta cells make up about 5-10% of the pancreatic islet cells and secrete somatostatin, which acts locally on neighbouring islet cells.
| Location | Pancreatic islets, often at the periphery |
|---|---|
| Secretes |
|
| Nerve Supply | Vagus nerve (parasympathetic); Coeliac plexus (sympathetic) |
| Blood Supply | Splenic artery branches; Pancreaticoduodenal arteries |
| Venous drainage |
|
| Lymphatic drainage |
|
Restrain the release of insulin and glucagon and slow digestion and absorption.
Somatostatinomas are very rare tumours causing diabetes, gallstones and fatty stools. Synthetic somatostatin analogues such as octreotide are used to treat hormone-secreting tumours and bleeding varices.
A rare delta cell tumour causing diabetes, gallstones and steatorrhoea.
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