The inferior mesenteric lymph nodes are pre-aortic nodes around the origin of the inferior mesenteric artery. They collect lymph from the hindgut (the distal third of the transverse colon, descending and sigmoid colon and upper rectum) after it passes through the colic, sigmoid and superior rectal nodes.
| Location | Pre-aortic, around the origin of the inferior mesenteric artery at about L3, and along its left colic, sigmoid and superior rectal branches |
|---|---|
| Receives lymph from | |
| Lymphatic drainage |
|
Filter lymph from the hindgut.
Surgery for left-sided colon and rectal cancer removes the mesentery and these nodes, often with high ligation of the inferior mesenteric artery to achieve a complete nodal harvest. Nodal involvement determines whether adjuvant chemotherapy is offered. Total mesorectal excision for rectal cancer removes the perirectal nodes that feed into this group.
Metastasis of sigmoid, descending colon or upper rectal cancer to nodes along the inferior mesenteric vessels.
Reactive enlargement of sigmoid mesenteric nodes in acute diverticulitis.
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