The superior longitudinal fasciculus is a large association bundle running front to back in the lateral hemisphere, above the insula, connecting the frontal lobe with the parietal and temporal lobes. It has several parts (SLF I, II and III), and the arcuate fasciculus is often treated as one of its components. It is the backbone of the frontoparietal networks for attention and action.
| Location | Deep lateral white matter of the frontal and parietal lobes, above the insula and lateral to the corona radiata |
|---|---|
| Parts |
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| Connections |
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| Blood Supply | Middle cerebral artery (deep branches); Anterior cerebral artery (medial part) |
Connects frontal and parietal areas for attention, spatial awareness, working memory, language and planning of movement.
Right-sided damage contributes to hemispatial neglect, while left-sided damage contributes to aphasia and apraxia. It is mapped with tractography before glioma surgery. White matter changes here relate to attention problems in ageing and some developmental disorders.
Inattention to the left side, linked to disconnection of the right superior longitudinal fasciculus.
Difficulty performing gestures, linked to left frontoparietal disconnection.
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