The splenium is the thick, rounded back end of the corpus callosum. Its fibres connect the occipital and posterior temporal and parietal lobes, curving back as the forceps major. It lies above the pineal gland and the great cerebral vein.
| Location | Posterior end of the corpus callosum, above the pineal gland and tectum |
|---|---|
| Parts |
|
| Connections |
|
| Blood Supply | Posterior cerebral artery (posterior pericallosal or splenial branches); Anterior cerebral artery (pericallosal artery) |
Connects the visual and posterior association areas of the two hemispheres so that both halves of the visual world are combined.
Splenium lesions can disconnect visual information from the language area; combined with left occipital damage this causes alexia without agraphia. Transient reversible lesions of the splenium can appear on MRI with seizures, antiepileptic drug changes, infections and metabolic disturbances. It is commonly involved in diffuse axonal injury.
Loss of reading with preserved writing, from left occipital damage plus splenium involvement.
A temporary splenial signal change on MRI linked to seizures, infection or metabolic causes, usually resolving.
Shearing damage that frequently affects the splenium in head trauma.
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