The posterior cingulate cortex is the back part of the cingulate gyrus, above the splenium of the corpus callosum. It is a central hub of the default mode network, active during rest and self-reflection.
| Location | Medial parietal region, posterior cingulate gyrus (Brodmann 23 and 31), continuous with the retrosplenial cortex |
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| Connections |
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| Blood Supply | Anterior cerebral artery (pericallosal branches); Posterior cerebral artery (parieto-occipital branches) |
Supports memory retrieval, self-referential thinking and orientation in space.
Reduced metabolism here is one of the earliest PET scan findings in Alzheimer disease. Damage to the retrosplenial area can cause difficulty finding the way in familiar places.
Early posterior cingulate hypometabolism on PET imaging.
Getting lost in familiar surroundings after retrosplenial damage.
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