Clarke nucleus (nucleus dorsalis or posterior thoracic nucleus) is a column of large neurons at the base of the dorsal horn from about C8 to L2-L3. It is the source of the dorsal spinocerebellar tract.
| Location | Medial base of the dorsal horn, lamina VII, from C8 to L2-L3 |
|---|---|
| Parts |
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| Connections |
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| Blood Supply | Posterior spinal arteries; Anterior spinal artery |
Relays unconscious position sense from the lower limb and trunk to the cerebellum.
Leg proprioceptive fibres entering below L3 ascend in the fasciculus gracilis to reach it. It degenerates in Friedreich ataxia, contributing to unsteady gait.
Inherited degeneration of spinocerebellar pathways, dorsal columns and Clarke nucleus causing progressive ataxia.
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