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Home › Body Atlas › Brain & Spinal Cord › Mesencephalic Nucleus of the Trigeminal Nerve
Brain Structure Head & Skull

Mesencephalic Nucleus of the Trigeminal Nerve

nucleus mesencephalicus nervi trigemini

The mesencephalic nucleus of the trigeminal nerve is a thin column of unusual sensory neurons in the midbrain and upper pons. It is the only place where primary sensory nerve cell bodies sit inside the brain rather than in a ganglion.

Anatomical Data

Structure & Connections

LocationAlong the side of the cerebral aqueduct and upper fourth ventricle, from the midbrain to the pons
Parts
  • Pseudounipolar sensory neurons
Connections
Blood SupplyPosterior cerebral and superior cerebellar artery branches
Biomechanics

Function & Actions

Carries position sense from the jaw muscles and teeth and drives the jaw jerk reflex.

Clinical Relevance

Clinical Notes

The jaw jerk reflex tested in examination depends on this nucleus; a brisk jaw jerk suggests upper motor neuron damage above the pons, as in motor neurone disease.

Pathology

Common Injuries & Conditions

Brisk Jaw Jerk

An exaggerated jaw reflex pointing to bilateral upper motor neuron disease.

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