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Home › Body Atlas › Brain & Spinal Cord › Dorsal Longitudinal Fasciculus
Brain Structure Head & Skull

Dorsal Longitudinal Fasciculus

fasciculus longitudinalis dorsalis

The dorsal longitudinal fasciculus is a thin fibre bundle that runs from the hypothalamus down through the periaqueductal grey and floor of the fourth ventricle. It links the hypothalamus with autonomic centres in the brainstem.

Anatomical Data

Structure & Connections

LocationPeriventricular grey matter from the hypothalamus through the midbrain to the medulla
Parts
  • Ascending and descending periventricular fibres
Connections
Blood SupplyPosterior cerebral and basilar artery branches
Biomechanics

Function & Actions

Carries hypothalamic control to brainstem centres for salivation, heart rate, gut function and other autonomic activity.

Clinical Relevance

Clinical Notes

Rarely damaged alone but contributes to autonomic disturbances in brainstem lesions.

Pathology

Common Injuries & Conditions

Autonomic Dysfunction in Brainstem Disease

Disturbed heart rate, blood pressure or gut control from damage to descending autonomic pathways.

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