The anterior cingulate cortex is the front part of the cingulate gyrus, curving around the front of the corpus callosum. It links emotion, motivation, attention and control of behaviour.
| Location | Medial frontal lobe, around the genu of the corpus callosum (Brodmann areas 24, 32, 33 and subgenual 25) |
|---|---|
| Parts |
|
| Connections | |
| Blood Supply | Anterior cerebral artery (callosomarginal and pericallosal branches) |
Detects errors and conflicts, weighs effort against reward, regulates emotion and processes the unpleasantness of pain.
Damage on both sides can cause severe apathy and akinetic mutism. The subgenual area is overactive in depression and is a target for deep brain stimulation, and cingulotomy has been used for intractable pain and obsessive-compulsive disorder.
Profound lack of movement and speech from bilateral anterior cingulate damage.
Mood disorder with abnormal activity in the subgenual cingulate cortex.
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